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These outcomes, along with a prior report showing that a little-molecule ACKR3 agonist CCX771 displays anxiolytic-like actions in mice,two assist the thought of targeting ACKR3 as a singular technique to modulate the opioid system, which could open new therapeutic avenues for opioid-similar Ailments.Tabernaemontana divaricata Conolidine can be an i